Students are introduced to pathophysiology and disease processes. The focus is on select structures and functions that support health and wellbeing, including fluid and electrolyte balance, acid-base balance, fatigue, sleep, thermoregulation, gas exchange, neuro/intracranial regulation, comfort/pain, infection, inflammation, and immunity. This course builds on pharmacological applications of select medication routes, calculations and medication safety, particularly related to intravenous therapy. Complementary therapies to manage pain are emphasized. Three-hour supervised lab practice is a required component of the course and clinical applications. Prerequisites: Successful completion of all semester three courses. Three credits.